

The reasons, which have given rise to this trend, include the availability, and accessibility of these medicines. The use of homoeopathic medicines as complements or alternatives to conventional medicines has been increasing worldwide. These mother tinctures contain a number of compounds in complex matrices in which no single active constituent is responsible for overall therapeutic effect. Therefore, it was considered worthwhile to evaluate the analgesic, anti inflammatory and anti arthritic activities of these mother tinctures in experimental animal models in order to prevent scientific basis for its use in Homoeopathy. These mother tinctures are prescribed for the treatment of analgesia and arthritis, but lacks scientific basis. Similarly, the mother tincture of Terminalia arjuna (TAMT) is used in various diseases of heart, angina pectoris, suffocation vertigo and gonorrhoea. Likewise the mother tincture of Bellis perennis (BPMT) is used for joint soreness, muscle soreness, soreness of abdominal wall and uterus, and in diarrhoea. Ricinus communis Mother tincture (RCMT) is used to relieve the symptoms of vertigo, burning sensation in stomach, diarrhoea and in inflamed anus.
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In Homoeopathy, mother tinctures are routinely prescribed for the treatment of wide variety of ailments such as Rauwolfia serpentina is used for high blood pressure, fever, sedation, stomach pain, skin problems, and muscular problems. Through this treatment, the disease progress can be slowed down, significant reduction in joint stiffness and pain can be achieved and further complications of the disease can be prevented. The medicines can reduce the frequency, duration and severity of the attacks and delay the onset of complications. Considering arthritis as constitutional problem and especially in early stages, the cases of RA respond well to the homoeopathic treatment.

There are many medicines reported in the literature for RA but there are very less preclinical or clinical data for these mother tinctures. It has been known for centuries that homoeopathic remedy if prescribed carefully for RA can be of a great help in relieving pain and increasing the mobility of the joint. In inflammatory reaction, increased cellularity of synovial tissue and joint damage are the pathological hallmarks of RA. Although there may be a plethora of systemic manifestations, the characteristic feature of RA is persistent inflammatory synovitis, usually involving peripheral joints in a symmetric distribution. Rheumatoid Arthritis (RA) is a progressive, disabling, chronic multisystem disease which is characterized by pain, swelling and stiffness of the synovial joints, which is often worse in the morning and after periods of inactivity. Role of homoeopathic mother tinctures in rheumatoid arthritis: An experimental study.
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How to cite this URL: Singh S, Karwasra R, Kalra P, Kumar R, Rani S, Nayak D, Gupta Y K. How to cite this article: Singh S, Karwasra R, Kalra P, Kumar R, Rani S, Nayak D, Gupta Y K. Keywords: Analgesic, Anti-arthritic, anti-inflammatory, Bellis perennis, Carrageenan, Curcuma longa, Homoeopathic mother tinctures, Rauwolfia serpentina, Ricinus communis, Terminalia arjuna, Tribulus terresteris All homoeopathic mother tinctures showed peripheral analgesic activities in hot plate induced thermal algesia in mice. Thus, revealed potent activity against inflammation. Result: Curcuma longa and Tribulus terresteris mother tinctures reduced hind paw swelling decreased the paw volume in Carrageenan treated rats. Arthritis was induced by Complete Freund's Adjuvant (CFA) injection in metatarsal footpad of Wistar albino rats.

Degree of inflammation was evaluated according to paw swelling. Materials and Methods: Paw oedema was induced by administration of 0.1ml 1% carrageenan in normal saline into right hind paw. Ricinus communis (RCMT), Rauwolfia serpentina (RSMT), Bellis perennis (BPMT), Curcuma longa (CLMT), Terminalia arjuna (TAMT) and Tribulus terresteris (TTMT). Objectives: The objective of present preliminary study was to assess the anti-inflammatory, analgesic and anti-arthritic effect of some homoeopathic mother tinctures viz.
